Target Discovery Strategies for Developing Innovative Immunotherapy | Fabiana Perna, MD, PhD

Fabiana Perna, MD, PhD
Associate Member, Attending Physician,
Department of   Blood and Marrow Transplant and Cellular Immunotherapy

Fabiana Perna is a physician-scientist focused on the pathogenesis and treatment of hematological disorders. She is an Associate Member in the Department of Blood and Marrow Transplant and Cellular Immunotherapy at Moffitt. Dr. Perna trained at Memorial Sloan Kettering Cancer Center under the mentorship of Drs. Stephen Nimer and Michel Sadelain.  She is the inventor of multiple patents on adoptive cellular therapy and competed for a number of awards such as the ASH scholar award, TRTH, Leukemia Research Foundation and more recently, she is the PI of a NIH/NCI R37 MERIT award and a NIH/NCI R21 grant. The Perna lab seeks to understand how genetic or molecular abnormalities impact the cancer surface proteome enabling the identification of novel targets for promoting leukemogenesis and use of immunotherapy.

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Dr. Perna’s Objectives:

At the end of the presentation, participants will be able to do the following

• Distinguish a tumor-associated target from a tumor specific target
• Revise CART T cell therapy toxicities beyond CRS and ICANS
• Identify the criteria of a suitable immunotherapeutic target

Faculty Disclosure

Dr. Perna has indicated that she has no relevant financial relationships with commercial interests.

Planning Committee Disclosure

Dr. Lekakis has indicated that he has no relevant financial relationships with commercial interests.

Target Audience

Faculty, Primary Care Physicians, APRNs, PharmD

Accreditation

The University of Miami Leonard M. Miller School of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Credit Designation

The University of Miami Leonard M. Miller School of Medicine designates this live activity for a maximum of 1 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1.0 MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.