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Clonal hematopoiesis as a predictor of clinical outcomes and adverse events in metastatic castration-resistant prostate cancer patients treated with androgen receptor-pathway inhibitors

March 15 @ 8:00 am - 9:00 am

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Dr. Catherine Callie Coombs, MD MS, UCI Health, CA

Dr. Catherine Callie Coombs is currently an Associate Clinical Professor at the University of California Irvine. She attended medical school at the University of Cincinnati College of Medicine. She completed her internship and residency at Duke University Medical Center in Durham. She subsequently completed a hematology and oncology fellowship at Memorial Sloan Kettering Cancer Center. She led the CLL program as an Assistant Professor at the University of North Carolina prior to moving to California in 2022 to be closer to family.

Her primary clinical focus is in the care of patients with chronic lymphocytic leukemia and small lymphocytic lymphoma. She has participated in multicenter studies examining the “real-world” implications of novel therapeutic agents on the lives of patients and has served as an investigator on a number of clinical trials, including both cooperative group studies and early-phase trials of novel agents. In addition to CLL, she sees other non-acute leukemias and has expertise in leukemia precursor states including clonal hematopoiesis (or “CHIP”) and CCUS.

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OBJECTIVES

At the end of the presentation, participants will be able to:

  • Examine the incidence of clonal hematopoiesis in a uniformly treated cohort of men with prostate cancer
  • Assess the clinical implications of clonal hematopoiesis on prostate cancer-specific outcomes
  • Explore the implications of clonal hematopoiesis on cardiovascular-specific adverse events in men on concurrent androgen-receptor pathway inhibitors

FACULTY DISCLOSURE:
Dr. Coombs has indicated she has the following relationships:

  • Consultant: AbbVie, AstraZeneca, Lilly, Beigene, Genentech, Janssen, MEI Pharma, Mingsight, Octapharma
  • Speaker: AbbVie, AstraZeneca, Beigene, Genentech

PLANNING COMMITTEE DISCLOSURE:

Dr. Lazaros Lekakis, Associate Professor, Cellular Therapy, has indicated that he has no relevant financial relationships with commercial interests.


TARGET AUDIENCE:
Faculty, Primary Care Physicians, APRNs, PharmD

ACCREDITATION:
The University of Miami Leonard M. Miller School of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

CREDIT DESIGNATION:
The University of Miami Leonard M. Miller School of Medicine designates this live activity for a maximum of 1 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1.0 MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

Details

Date:
March 15
Time:
8:00 am - 9:00 am
Series:
Event Categories:
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Organizer

Gabriela Suarez
Phone
305-243-9528
Email
gps63@miami.edu