“Allan-Herndon-Dudley Syndrome: From Gene Discovery To Therapeutic Horizons” (Hybrid Event)

Roy E. Weiss, MD, PhD

Professor of Medicine; Chair, Department of Medicine; Kathleen & Stanley Glaser Distinguished Chair in Medicine; Rabbi Morris I. Esformes Endowed Chair in Medicine and Endocrinology

University of Miami Miller School of Medicine

Roy E. Weiss, M.D., Ph.D., is the Kathleen & Stanley Glaser Distinguished Chair in Medicine, Rabbi Morris I. Esformes Endowed Chair in Medicine and Endocrinology and Chairman of the Department of Medicine at the University of Miami Miller School of Medicine. He is also the Chief Medical Officer of Ambulatory Services for UHealth.

Board certified in endocrinology, diabetes and metabolism, Dr. Weiss is an expert in diseases of the thyroid. He has an active clinical practice and is sought out as one of the leading experts of genetic thyroid disease. His research focuses on the mechanisms of thyroid hormone action at the molecular, physiological, and psychological levels for which he holds several patents and over 180 peer-reviewed articles and book chapters.

Dr. Weiss currently serves as Principal Investigator (PI) on a grant from the National Institute of Health Disparities with the aim of identifying modifiable factors in health disparities for patients with cardiovascular disease, obesity, and diabetes.

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Objectives

• Evaluate genetic and molecular mechanisms underlying the Allen Herndon Dudley Syndrome, including how mutations in the MCT8 gene affect thyroid hormone transport and result in the clinical manifestations observed in patients.
• Assess current and emerging therapeutic approaches.
• Assess the importance of thyroid hormone transport on neurologic and metabolic processes.

Faculty Disclosures

Dr. Weiss has indicated the following relevant financial relationships with commercial interests:

• Advisor – Prizm Therapeutics
• Advisor – Fortress Pharmaceuticals

Planning Committee Disclosure

Dr. Deshpande has indicated the following relevant financial relationships with commercial interests:

• Advisor – GI Health Foundation

Dr. Weiss, the speaker for this session, is also a member of the planning committee. His disclosures are indicated above.

Target Audience

Primary care physicians.

Accreditation

The University of Miami Leonard M. Miller School of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Credit Designation

The University of Miami Leonard M. Miller School of Medicine designates this live activity for a maximum of 1 AMA PRA Category 1 Credit™.   Physicians should claim only the credit commensurate with the extent of their participation in the activity. Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1.0 MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.”