“A Joint Endeavor: Challenges in Periprosthetic Joint Infection” (Hybrid Event)

Sandra B. Nelson, MD

Assistant Professor of Medicine; Clinical Director, Division of Infectious Diseases

Massachusetts General Hospital

Sandra Nelson MD is an Infectious Diseases physician at Massachusetts General Hospital (MGH) and an Associate Professor at Harvard Medical School. She completed her medical school at Duke University School of Medicine, followed by residency training in Internal Medicine and Pediatrics at the University of Michigan Medical Center. She completed her fellowship training in Infectious Diseases at Johns Hopkins University before joining the faculty at MGH and Harvard Medical School in 2007.

At MGH, Dr. Nelson is a Clinical Director of the Division of Infectious Diseases.  She also directs the Program in Outpatient Parenteral Antimicrobial Therapy (OPAT) and is a co-director of the highly acclaimed Harvard CME course on Infectious Diseases in Adults.  Her academic interest is in the care of patients with musculoskeletal infections; at MGH she directs the Program in Musculoskeletal Infectious Diseases which is actively engaged in clinical care, educational efforts, and in research on treatment and prevention of musculoskeletal infection.  She was a delegate to the 2013 and 2018 International Consensus Meetings (ICM) on Periprosthetic Joint Infections, where she worked to create a new working definition of periprosthetic shoulder infections.  She is also serving as a delegate to the 2025 ICM and working on the international unified Periprosthetic joint infection diagnosis guidelines.  She is a Past-President of the Musculoskeletal Infection Society (MSIS) and is a Section Editor at UpToDate® for the musculoskeletal infection and skin and soft tissue infection chapters.

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Objectives

• Evaluate the increasing burden and impact of periprosthetic joint infection (PJI) in 2025.
• Analyze the role of oral antimicrobial therapy in treating bone and joint infection, including PJI.
• Propose evidence-based strategies to prevent periprosthetic joint infection.

Faculty Disclosures

Dr. Nelson has indicated she has no relevant financial relationships with commercial interests.

Planning Committee Disclosure

Dr. Deshpande has indicated the following relevant financial relationships with commercial interests:

• Advisor – GI Health Foundation

Dr. Weiss has indicated the following relevant financial relationships with commercial interests:

• Advisor – Prizm LLC
  
• Advisor – Fortress Pharmaceuticals

Laura Pinzon has indicated she has no relevant financial relationships with commercial interests.

Target Audience

Primary care physicians.

Accreditation

The University of Miami Leonard M. Miller School of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Credit Designation

The University of Miami Leonard M. Miller School of Medicine designates this live activity for a maximum of 1 AMA PRA Category 1 Credit™.   Physicians should claim only the credit commensurate with the extent of their participation in the activity. Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1.0 MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.”